The start of this race is in the historic center of Zuoz. Via La Resgia, the route follows the golf course in the direction of Madulain and soon joins the EUT102 route.

Then the steep ascent to Munt Seja begins, where you will be surprised by a breathtaking panorama with a view of Zernez. Via Lej da Prastinaun and Alp Arpiglia it goes down into the valley to the refreshment point in Zuoz, La Resgia. Then the route passes through the historic center of Zuoz, probably the most beautiful in the whole of the Engadin.

The hard ascent to Chamanna d'Es-cha, the highest point of this route, begins in the village. From the Chamanna d'Es-cha you have a wonderful view of the Bernina massif. Freshly fed, you follow the high path under the flank of Piz Kesch along to Fuorcla Gualdauna and across the Val d'Alvra down towards La Punt. There the route joins the Via Engiadina, a wonderful trail towards Bever, where the next refreshment station is waiting.

Strengthened, the final ascent to Alp Muntatsch and on via the Padella Panorama Trail with its unique view, again in the direction of the Bernina massif, to Marguns. From Marguns there is a descent towards Samedan, where the well-deserved destination is in the Promulins Arena.

The EUT53 is completed on the principle of partial self-sufficiency. The participants eat independently between the posts and have the obligatory material according to the competition regulations with them along the entire route.